Covid-19 Vaccine- Scientists Find The Culprit Behind The Allergic Reaction

Covid-19 Vaccine Allergy
Covid-19 Vaccine Allergy

News reports about the allergic reactions have made an issue, urging people who have a history of “significant” allergic reactions not get the Pfizer-BioNTech Covid-19 vaccine.

Scientists think polyethylene glycol, or PEG, could be responsible for allergic reactions to the Pfizer-BioNTech vaccine.

While the United States on Wednesday secured a deal with Pfizer Inc, for an additional 100 million doses for its Covid-19 vaccine, the cases of allergic reactions have reportedly found. For a reason, scientists think Polyethylene glycol, or PEG, could be responsible for allergic reactions to the Pfizer- BioNTech vaccine: the compound polyethylene glycol, also known as PEG. 

PEG has never been used before in an approved vaccine, but it is found in many drugs that have occasionally triggered anaphylaxis- a life-threatening reaction that can cause rashes, a plummeting blood pressure, shortness of breath, and fast heartbeat. At the same time, some allergists and immunologists believe a small number of people previously exposed to PEG may have a high level of antibodies against PEG, putting them at risk of an anaphylactic reaction to the vaccine.

Six severe allergic reactions to the vaccine have been reported in the U.S. as per the reports from the Centers for Disease Control. The UK regulators have already issued an advisory regarding the issue, urging people who have a history of allergic reactions not to get the vaccine. 

The United States had started the immunization drive against the Covid-19 began on 14, December because of the hike of disease FDA (Foods and Drugs Administration) granted emergency authorization to Pfizer-BioNTech followed by Moderna. Under the new agreement for additional doses of Pfizer’s 

Prof Peter Openshaw, an expert in immunology at Imeperial College London, said “ The fact that we know so soon about these two allergic reactions that the regulator has acted on this to issue precautionary advice shows that this monitoring system is working well.” 

Such reactions is quite common among new vaccines and are treated with drugs such as steroids or adrenaline.